Large efforts that combine many python modules or apps. Examples include Django, django-cms, and Mezzanine. Most CMSes fall into this category, and so do storefronts.

# Using ThisDevelopment StatusNameCommitsVersionStarsForks
  413Production/StableDjango2.2.54411418972
  75Production/StableWagtail CMS2.6.278601709
  177Production/Stabledjango CMS3.6.070322362
  33Betacookiecutter-django1.11.957901566
  36Saleor55802104
  10Open edX45372494
  179Betadjango-oscar2.0.139581506
  117Production/StableMezzanine4.3.139211427
  5syte2852537
  49BetaPinax0.72473449
  44Unknowndjango SHOP1.0.21964700
  4Production/Stabledjango-angular2.2.11212301
  7Betaralph2.3.11167329
  10Production/Stableshuup2.0.01007526
  2BetaEvennia0.6983431
  12django-twoscoops-project865369
  6cookiecutter-django-rest784125
  4Production/StableDjango Vanilla Views1.0.677662
  1Production/Stablerestless2.1.176985
  50Production/StablefeinCMS1.16.4764225
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